Resolution of night terrors after discontinuation of cetirizine

We present a 4-year-old girl with allergies and asthma who developed night terrors after initiation of montelukast at 2 years of age. Montelukast was discontinued and cetirizine was started. Nigh terrors persisted. Sleep diaries were collected and diagnosticpolysomnogram (PSG) was ordered. Sleep diaries revealed an average sleep time of 10 hours with night terrors occurring three nights a week approximately two hours after sleep onset. The PSG did not show evidence of sleep disordered breathing or periodic leg movements. Cetirizine was discontinued and the night terrors ceased. Upon re-introduction of the medication, the sleep terrors recurred.